Interleukin-2 Receptor

Preferred Label : Interleukin-2 Receptor;

NCIt synonyms : Interleukin 2 Receptor; IL2 Receptor; IL-2 Receptor; IL2R; IL-2R; High Affinity Interleukin-2 Receptor;

NCIt definition : A heterotrimeric protein found on the cell surface of immune cells that binds to interleukin-2. This receptor is comprised of alpha, beta and gamma subunits; the alpha and beta subunits bind interleukin-2 while the downstream ligand-dependent signaling is mediated by the gamma subunit.;

Details

Origin ID

C104679;

UMLS CUI

C0034819;

Automatic exact mappings (from CISMeF team)
- Interleukin 2 receptor [LOINC component]
- Interleukin 2 receptor, alpha [OMIM gene]
- Interleukin-2 receptor (substance) [SNOMED CT concept]
- interleukin 2 receptor subunit alpha [ORDO Gene]
- interleukin-2 receptor activity [GO term]
- receptors, Interleukin-2 [MeSH concept]
- receptors, interleukin-2 [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Interleukin 2 receptor [LOINC component]
- Interleukin-2 receptor (substance) [SNOMED CT concept]
- interleukin-2 receptor site [SNOMED Notion]
- receptors, Interleukin-2 [MeSH concept]
- receptors, interleukin-2 [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Adargileukin Alfa [NCIt concept]
- Aerosolized Aldesleukin [NCIt concept]
- Aldesleukin [NCIt concept]
- Anti-PD-1/IL-2 Bispecific Antibody Fusion Protein IBI363 [NCIt concept]
- Bempegaldesleukin [NCIt concept]
- CD122-selective IL-2/Anti-CD25 Antibody-like Fusion Protein ANV419 [NCIt concept]
- IL-2 Superkine-Recombinant Human Albumin Fusion Protein MDNA11 [NCIt concept]
- IL-2/Anti-IL-2 Antibody Conjugate SLC-3010 [NCIt concept]
- Interleukin-2 Jurkat Derived [NCIt concept]
- Interleukin-2 Liposome [NCIt concept]
- Low-dose Aldesleukin ILT-101 [NCIt concept]
- Modified Interleukin-2 DF6215 [NCIt concept]
- Modified Interleukin-2 LTC004 [NCIt concept]
- PEG-interleukin-2 [NCIt concept]
- Pegenzileukin [NCIt concept]
- Pegylated CD25/CD122-selective Interleukin-2 Mutein STK-012 [NCIt concept]
- Pegylated IL-2 8MW2311 [NCIt concept]
- Pegylated Orthogonal IL-2 STK-009 [NCIt concept]
- Protein-engineered Interleukin-2 XTX202 [NCIt concept]
- Recombinant Interleukin-2 [NCIt concept]
- Rezpegaldesleukin [NCIt concept]
- Ribocytokine IL-2 BNT153 [NCIt concept]
- Teceleukin [NCIt concept]
- TransCon IL-2 Beta/Gamma [NCIt concept]
gene_product_has_biochemical_function
- Cytokine Receptor [NCIt concept]
gene_product_plays_role_in_biological_process
- B Cell Proliferation [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- T-Cell Proliferation [NCIt concept]
has_gene_product_element
- Cytokine Receptor Common Subunit Gamma [NCIt concept]
- Interleukin-2 Receptor Subunit Alpha [NCIt concept]
- Interleukin-2 Receptor Subunit Beta [NCIt concept]
is_target
- Aerosolized Aldesleukin [NCIt concept]
- Aldesleukin [NCIt concept]
- DI-Leu16-IL2 Immunocytokine [NCIt concept]
- Denileukin Diftitox [NCIt concept]
- IL-2/IL-12-based Fusion Protein CLN-617 [NCIt concept]
- Protein-engineered Interleukin-2 XTX202 [NCIt concept]
- Recombinant Interleukin-2 [NCIt concept]
- SBIL-2 Transduced Autologous Tumor-Infiltrating Lymphocyte [NCIt concept]
- Technetium Tc 99 Hydrazinonicotinamide-Tricine-linked Interleukin-2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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