Modified Interleukin-2 DF6215

Preferred Label : Modified Interleukin-2 DF6215;

NCIt synonyms : Modified IL-2 DF6215;

NCIt definition : A modified and recombinant form of the human endogenous cytokine interleukin-2 (IL-2), with potential immunostimulating and antineoplastic activities. Upon administration, modified IL-2 DF6215 targets and binds to IL-2 receptor (IL-2R) expressed on CD8 T effector cells and activates IL-2R-mediated signaling. This enhances cytotoxic T-lymphocytes (CTLs)-mediated cytotoxic immune responses against tumor cells.;

Molecule name : DF-6215; DF 6215;

Details

Origin ID

C203655;

chemical_or_drug_affects_gene_product
- Interleukin-2 Receptor [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Cytokine Receptor Activation [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Gene Regulation Process [NCIt concept]
- Immunopotentiation [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Intercellular Communication Induction [NCIt concept]
- Lymphocyte Activation Process [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients