Transforming Growth Factor

Preferred Label : Transforming Growth Factor;

NCIt synonyms : Tumor Growth Factors; TGF;

NCIt definition : Transforming Growth Factors are a family of extracellular signaling peptides involved in cell growth stimulation. Found in hematopoietic tissue, various TGF-beta subtypes stimulate wound healing and may inhibit lymphopoiesis and myelopoiesis. TGF-alpha binds to EGFR and stimulates endothelial cell growth.;

Details

Origin ID

C20453;

UMLS CUI

C0040691;

Automatic exact mappings (from CISMeF team)
- left-right determination factor 2 [HGNC gene]
Biochemical function of gene products
- Artemin [NCIt concept]
- Bone Morphogenetic Protein [NCIt concept]
- Bone Morphogenetic Protein 1 [NCIt concept]
- Bone Morphogenetic Protein 10 [NCIt concept]
- Bone Morphogenetic Protein 15 [NCIt concept]
- Bone Morphogenetic Protein 2 [NCIt concept]
- Bone Morphogenetic Protein 3 [NCIt concept]
- Bone Morphogenetic Protein 3B [NCIt concept]
- Bone Morphogenetic Protein 4 [NCIt concept]
- Bone Morphogenetic Protein 5 [NCIt concept]
- Bone Morphogenetic Protein 6 [NCIt concept]
- Bone Morphogenetic Protein 7 [NCIt concept]
- Bone Morphogenetic Protein 8B [NCIt concept]
- Growth/Differentiation Factor 11 [NCIt concept]
- Growth/Differentiation Factor 15 [NCIt concept]
- Growth/Differentiation Factor 2 [NCIt concept]
- Growth/Differentiation Factor 3 [NCIt concept]
- Growth/Differentiation Factor 5 [NCIt concept]
- Growth/Differentiation Factor 8 [NCIt concept]
- Growth/Differentiation Factor 9 [NCIt concept]
- Left-Right Determination Factor 1 [NCIt concept]
- Left-Right Determination Factor 2 [NCIt concept]
- Muellerian-Inhibiting Factor [NCIt concept]
- Neurturin [NCIt concept]
- Nodal Homolog [NCIt concept]
- Protransforming Growth Factor Alpha [NCIt concept]
- Transforming Growth Factor Alpha [NCIt concept]
- Transforming Growth Factor Beta-1 [NCIt concept]
- Transforming Growth Factor Beta-2 [NCIt concept]
- Transforming Growth Factor Beta-3 [NCIt concept]
- Transforming Growth Factor-Beta Superfamily [NCIt concept]
Currated CISMeF NLP mapping
- transforming growth factors [MeSH Descriptor]
- transforming growth factors [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- transforming growth factors [MeSH concept]
- transforming growth factors [MeSH Descriptor]
gene_product_has_biochemical_function
- Growth Factor [NCIt concept]

Keyword's position in hierarchy(ies) :

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