Left-Right Determination Factor 2

Preferred Label : Left-Right Determination Factor 2;

NCIt synonyms : Endometrial Bleeding-Associated Factor; Transforming Growth Factor Beta 4; EBAF; Transforming Growth Factor, Beta-4; LEFTY 1, Mouse, Homolog of; TGF-Beta-4; Left-Right Determination Factor A; LEFTY1; LEFTYA; LEFTA; LEFTY2; Lefty-A Protein; Transforming Growth Factor, Beta-4 (Endometrial Bleeding-Associated Factor; LEFTY A); LEFTY A; TGF-Beta 4; TGFB4; Protein Lefty-A; Transforming Growth Factor Beta-4; Protein Lefty-2; Endometrial Bleeding Associated Factor;

NCIt definition : Left-right determination factor 2 (366 aa, 41 kDa) is encoded by the human LEFTY2 gene. This protein is involved in the determination of left-right organ symmetry during embryogenesis.;

NCIt note : Left-right determination factor 2 is transiently expressed before and during menstrual bleeding and may also play a role in endometrial bleeding.;

Details

Origin ID

C26130;

UMLS CUI

C0916169;

Automatic exact mappings (from CISMeF team)
- LEFTY2 protein, human [MeSH Supplementary Concept]
- LEFTY2 protein, human [MeSH concept]
- Left-Right determination factor 2 [MeSH concept]
- Left-Right determination factors [MeSH concept]
- Left-Right determination factors [MeSH Descriptor]
- Left-right determination factor 1 [OMIM gene]
- Left-right determination factor 2 [OMIM gene]
- left-right determination factor 2 [HGNC gene]
- left-right determination factor 2 [ORDO Gene]
- transforming growth factor beta4 [MeSH concept]
- transforming growth factor beta4 [MeSH Supplementary Concept]
OMIM relation
- Left-right determination factor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- LEFTY2 protein, human [MeSH Supplementary Concept]
- LEFTY2 protein, human [MeSH concept]
gene_encodes_gene_product
- Growth Factor Gene [NCIt concept]
- LEFTY2 Gene [NCIt concept]
- Transforming Growth Factor-Beta Family Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Transforming Growth Factor [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_biomarker_type
- Disease Marker [NCIt concept]
gene_product_is_element_in_pathway
- TGF-beta Signaling Pathway KEGG [NCIt concept]
gene_product_malfunction_associated_with_disease
- Infertility [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Organogenesis [NCIt concept]
- Pattern Formation [NCIt concept]
- Receptor Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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