" /> Growth/Differentiation Factor 8 - CISMeF





Preferred Label : Growth/Differentiation Factor 8;

NCIt synonyms : GDF-8; GDF8; Myostatin; Growth Differentiation Factor-8;

NCIt definition : Growth/differentiation factor 8 (375 aa, 43 kDa) is encoded by the human MSTN gene. This protein plays a role in the negative regulation of skeletal muscle growth.;

NCIt note : The active growth factor is released from the precursor following proteolytic cleavage at arginine at amino acid position 266 which is the final amino acid in a polybasic proteolytic processing site. (EntrezGene and UniProt); Growth/Differentiation Factor 8 may be a treatment for cachexia in cancer patients.;

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31/07/2025


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