MeSH definition : Hormonally active polypeptides that can induce the transformed phenotype when added
to normal, non-transformed cells. They have been found in culture fluids from retrovirally
transformed cells and in tumor-derived cells as well as in non-neoplastic sources.
Their transforming activities are due to the simultaneous action of two otherwise
unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR
BETA.;
Hormonally active polypeptides that can induce the transformed phenotype when added
to normal, non-transformed cells. They have been found in culture fluids from retrovirally
transformed cells and in tumor-derived cells as well as in non-neoplastic sources.
Their transforming activities are due to the simultaneous action of two otherwise
unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR
BETA.