transforming growth factors

Preferred Label : transforming growth factors;

MeSH definition : Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA.;

MeSH synonym : factors, transforming growth; growth factors, transforming; transforming growth factor; factor, transforming growth; growth factor, transforming;

MeSH CAS label : animal growth regulators, transforming growth factors;

Registry Number MeSH : 76057-06-2;

MeSH annotation : general or unspecified; prefer specifics;

Wikipedia link : https://en.wikipedia.org/wiki/Transforming growth factor;

Is substance : O;

Details

Origin ID

D015291;

UMLS CUI

C0040691;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- left-right determination factor 2 [HGNC gene]
Currated CISMeF NLP mapping
- Recombinant Transforming Growth Factor [NCIt concept]
- Transforming Growth Factor [NCIt concept]
Indexing information
- simian sarcoma virus transformation-specific glycopeptide [MeSH Supplementary Concept]
Record concept(s)
- transforming growth factors [MeSH concept]
Related MeSH Supplementary Concept(s)
- dorsalin 1 protein, gallus gallus [MeSH Supplementary Concept]
- dorsalin 1 protein, rat [MeSH Supplementary Concept]
- transforming growth factor type e [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Transforming Growth Factor [NCIt concept]

Keyword's position in hierarchy(ies) :

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