Preferred Label : Recombinant Transforming Growth Factor;
NCIt synonyms : Tumor Growth Factors; Transforming Growth Factor; TGF; Therapeutic Transforming Growth Factor;
NCIt definition : A recombinant therapeutic agent which is chemically identical to or similar to endogenous
transforming growth factor (TGF). Representing peptides of two distinct classes, designated
TGF-alpha and TGF-beta, TGFs are produced by various non-transformed cells during
the development of mammalian embryos and are found in urine and plasma; TGFs are also
produced by some human carcinomas and cell lines transformed by viral and cellular
oncogenes. TGFs affect bone formation and remodeling by inhibition of the synthesis
of collagen and release of calcium. (NCI04);
CAS number : 76057-06-2;
Origin ID : C899;
UMLS CUI : C1527194;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Semantic type(s)
