Growth/Differentiation Factor 9

Preferred Label : Growth/Differentiation Factor 9;

NCIt synonyms : GDF-9 Protein; GDF9; GDF9 Protein; GDF-9; Growth Differentiation Factor 9; Growth Differentiation Factor-9;

NCIt definition : Growth/differentiation factor 9 (454 aa, 51 kDa) is encoded by the human GDF9 gene. This protein plays a role in folliculogenesis.;

NCIt note : The active growth factor is released from the precursor following proteolytic cleavage at arginine at amino acid position 319 which is the final amino acid in a polybasic proteolytic processing site. (EntrezGene and UniProt);

Details

Origin ID

C26375;

UMLS CUI

C1686883;

Currated CISMeF NLP mapping
- growth differentiation factor 9 [MeSH Descriptor]
- growth differentiation factor 9 [MeSH concept]
OMIM relation
- Growth/differentiation factor 9 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- GDF9 protein, human [MeSH concept]
- GDF9 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- GDF9 Gene [NCIt concept]
- Growth Factor Gene [NCIt concept]
- Transforming Growth Factor-Beta Family Gene [NCIt concept]
gene_product_expressed_in_tissue
- Oocyte [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
- Ovary [NCIt concept]
gene_product_has_biochemical_function
- Transforming Growth Factor [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_biomarker_type
- Disease Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Morphogenesis [NCIt concept]
- Receptor Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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