Neurturin - CISMeF

Preferred Label : Neurturin;

NCIt synonyms : NRTN; Prepro-Neurturin;

NCIt definition : Neurturin (197 aa, 22 kDa) is encoded by the human NRTN gene. This protein may be involved in both the development of the nervous system and the survival of sympathetic neurons.;

NCIt note : The active form of neurturin is produced by proteolytic cleavages that remove 95 N-terminal amino acids from the full length precursor protein. (UniProt); Neurturin signals through RET and a GPI-linked coreceptor. (EntrezGene);

Details

Origin ID

C28466;

UMLS CUI

C1531001;

Currated CISMeF NLP mapping
- neurturin [MeSH Descriptor]
- neurturin [MeSH concept]
OMIM relation
- Neurturin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NRTN protein, human [MeSH concept]
- NRTN protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Growth Factor Gene [NCIt concept]
- NRTN Gene [NCIt concept]
- Transforming Growth Factor-Beta Family Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Neurotrophic Factor [NCIt concept]
- Transforming Growth Factor [NCIt concept]
gene_product_is_biomarker_type
- Disease Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation Regulatory Process [NCIt concept]
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Neural Development [NCIt concept]
- Receptor Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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