Neurotrophic Factor

Preferred Label : Neurotrophic Factor;

NCIt synonyms : Neurotrophin;

NCIt definition : A family of protein growth factors produced by the nervous system and peripheral target tissues. These proteins are critical for development, growth, regeneration, survival, and differentiation of neurons.;

NCIt note : Neurotrophin signaling is mediated by the Trk family of receptor tyrosine kinases. (IP, N. Y. (1998), The Neurotrophins and Neuropoietic Cytokines: Two Families of Growth Factors Acting on Neural and Hematopoietic Cells. Annals of the New York Academy of Sciences, 840: 97-106. doi: 10.1111/j.1749-6632.1998.tb09553.x);

Details

Origin ID

C20391;

UMLS CUI

C0132298;

Biochemical function of gene products
- Artemin [NCIt concept]
- Brain-Derived Neurotrophic Factor [NCIt concept]
- Glucose-6-Phosphate Isomerase [NCIt concept]
- Neurturin [NCIt concept]
Currated CISMeF NLP mapping
- nerve growth factors [MeSH Descriptor]
- nerve growth factors [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Growth Factor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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