Delta-Like Protein 3

Preferred Label : Delta-Like Protein 3;

NCIt synonyms : Delta3; DLL3; Delta 3; Drosophila Delta Homolog 3; Delta-Like 3;

NCIt definition : Delta-like protein 3 (618 aa, 65 kDa) is encoded by the human DLL3 gene. This protein is involved in binding to notch proteins, mesoderm development and neurogenesis.;

Details

Origin ID

C104256;

UMLS CUI

C1565945;

OMIM relation
- Delta-like canonical notch ligand 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- DLL3 protein, human [MeSH Supplementary Concept]
- DLL3 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DLL3 Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Notch Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Signal Transduction [NCIt concept]
is_target
- Anti-DLL3 ADC ZL-1310 [NCIt concept]
- Anti-DLL3 CAR-NK Cells [NCIt concept]
- Anti-DLL3/Anti-CD47 Bispecific Antibody PT217 [NCIt concept]
- Anti-DLL3/CD3 Bispecific Antibody BI 764532 [NCIt concept]
- Anti-DLL3/CD3 Bispecific Antibody QLS31904 [NCIt concept]
- Anti-DLL3/CD3/CD137 Trispecific Antibody RG6524 [NCIt concept]
- Anti-DLL3/DLL3/CD3 Trispecific Antibody ZG006 [NCIt concept]
- Antibody-drug Conjugate SC-002 [NCIt concept]
- Autologous Anti-DLL3 CAR-T Cells LB2102 [NCIt concept]
- CAR T-Cells AMG 119 [NCIt concept]
- DLL3/CD3e Tri-specific T-cell Activating Construct HPN328 [NCIt concept]
- Rovalpituzumab Tesirine [NCIt concept]
- Tarlatamab [NCIt concept]
- Zirconium Zr 89-DFO-SC16.56 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients