ARAF wt Allele

Preferred Label : ARAF wt Allele;

NCIt synonyms : A-Raf Proto-Oncogene, Serine/Threonine Kinase wt Allele; ARAF1; PKS2; RAFA1; PKS; ARAF1 Gene; v-raf Murine Sarcoma 3611 Viral Oncogene Homolog 1 Gene; Oncogene PKS; ARAF1 wt Allele; A-RAF; Oncogene ARAF1;

NCIt definition : Human ARAF1 wild-type allele is located within Xp11.4-p11.2 and is approximately 11 kb in length. This allele, which encodes A-Raf proto-oncogene serine/threonine-protein kinase protein, plays a role in the transduction of mitogenic signals from the cell membrane to the nucleus.;

GenBank Accession Number : NM_001654;

Details

Origin ID

C51190;

UMLS CUI

C1705956;

OMIM relation
- Araf protooncogene, serine/threonine kinase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_associated_with_disease
- Lymphoproliferative Disorder [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- X: 47176761-47187553 [NCIt concept]
gene_in_chromosomal_location
- Xp11.2-p11.4 [NCIt concept]
gene_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Bladder Cancer Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- Colorectal Cancer Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Glioblastoma Multiforme Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- Melanoma Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Non-Small Cell Lung Cancer Pathway [NCIt concept]
- Pancreatic Cancer Pathway [NCIt concept]
- Progesterone-Mediated Oocyte Maturation Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Proliferation [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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