CD28 wt Allele

Preferred Label : CD28 wt Allele;

NCIt synonyms : T44; CD28 Molecule wt Allele; CD28 Antigen (Tp44) Gene; Tp44;

NCIt definition : Human CD28 wild-type allele is located within 2q33 and is approximately 31 kb in length. This allele, which encodes T-cell-specific surface glycoprotein CD28 protein, is involved in the costimulation that is essential for CD4 -positive T-cell proliferation, survival, interleukin-2 production, and T-helper type-2 (Th2) development.;

GenBank Accession Number : NM_006139;

Details

Origin ID

C51118;

UMLS CUI

C1707096;

Automatic exact mappings (from CISMeF team)
- 1-benzoyl-2-(naphth-1-ylamino)ethene [MeSH Supplementary Concept]
- Antigen cd28 [OMIM gene]
OMIM relation
- Antigen cd28 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 2: 204396704-204428062 [NCIt concept]
gene_in_chromosomal_location
- 2q33 [NCIt concept]
gene_is_element_in_pathway
- Allograft Rejection Pathway [NCIt concept]
- Antigen Dependent B Cell Activation Pathway [NCIt concept]
- Autoimmune Thyroid Disease Pathway [NCIt concept]
- Bystander B Cell Activation Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Cytotoxic T Cell Surface Pathway [NCIt concept]
- Graft-Versus-Host Disease Pathway [NCIt concept]
- HIV Induced T Cell Apoptosis Pathway [NCIt concept]
- Intestinal IgA Production Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T Helper Cell Surface Molecule Pathway [NCIt concept]
- T-Cell Activation Co-Stimulatory Signaling Pathway [NCIt concept]
- T-Cell Activation Pathway [NCIt concept]
- T-Cell Polarization Pathway [NCIt concept]
- Th1/Th2 Differentiation Pathway [NCIt concept]
- Type I Diabetes Mellitus Pathway [NCIt concept]
- Viral Myocarditis Pathway [NCIt concept]
gene_plays_role_in_process
- Intercellular Communication Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- T-Cell Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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