Cyclin-Dependent Kinase Inhibitor 1

Preferred Label : Cyclin-Dependent Kinase Inhibitor 1;

NCIt synonyms : MDA 6; CDKN1A Protein; p21; CIP-1 Protein; Cyclin-Dependent Kinase Inhibitor 1A; WAF-1 Protein; CDK-Interacting Protein 1; CDKN1A; Melanoma Differentiation-Associated Protein 6; Cyclin-Dependent Kinase Inhibitor-1A; p21Cip1/Waf1; p21CIP1; MDA-6; Waf1p21;

NCIt definition : Cyclin-dependent kinase inhibitor 1 (164 aa, 18 kDa) is encoded by the human CDKN1A gene. This protein is involved in cell cycle arrest.;

Details

Origin ID

C17783;

UMLS CUI

C1529821;

OMIM relation
- Cyclin-dependent kinase inhibitor 1a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CDKN1A protein, human [MeSH concept]
- CDKN1A protein, human [MeSH Supplementary Concept]
- Cyclin-Dependent kinase inhibitor p21 [MeSH Descriptor]
- Cyclin-Dependent kinase inhibitor p21 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CDKN1A Gene [NCIt concept]
- Cell Cycle Gene [NCIt concept]
- Cyclin-Dependent Kinase Inhibitor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Enzyme Inhibitor Protein [NCIt concept]
- Regulatory Protein [NCIt concept]
- Tumor Suppressor Protein [NCIt concept]
gene_product_is_biomarker_type
- Tumor Marker [NCIt concept]
gene_product_is_element_in_pathway
- ATM Signaling Pathway [NCIt concept]
- Calcineurin Pathway [NCIt concept]
- Cell Cycle Pathway [NCIt concept]
- Cyclin Regulation of Cell Cycle Pathway [NCIt concept]
- Erythropoietin Neuroprotection Pathway [NCIt concept]
- G1 to S Transition Pathway [NCIt concept]
- G1/S Checkpoint Pathway [NCIt concept]
- G2/M Checkpoint Pathway [NCIt concept]
- Hypoxia Pathway [NCIt concept]
- p53 Signaling Pathway BioCarta [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Negative Regulation of G1 Phase [NCIt concept]
is_target
- p21 Gene Activator saRNA RAG-01 [NCIt concept]

Keyword's position in hierarchy(ies) :

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