Preferred Label : p21 Gene Activator saRNA RAG-01;
NCIt definition : A small activating RNA (saRNA) targeting the tumor suppressor gene p21, with potential
antineoplastic activity. Upon intravesical instillation of p21 gene activator saRNA
RAG-01, the saRNA targets and activates the expression of the p21 gene and restores
p21 therapeutic protein levels. This may decrease bladder tumor cell growth. Downregulation
of p21 plays a key role in tumorigenesis. p21 is crucial for regulating the progression
of the cell cycle and plays an essential role in halting the proliferation of cancer
cells.;
Molecule name : RAG 01; RAG-01;
Origin ID : C215089;
concept_is_in_subset
- has_target
