Cyclin-Dependent kinase inhibitor p21

Preferred Label : Cyclin-Dependent kinase inhibitor p21;

MeSH definition : A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN-DEPENDENT KINASES and associates with PROLIFERATING CELL NUCLEAR ANTIGEN and CASPASE 3.;

MeSH synonym : cyclin kinase inhibitor p21; cdk2-associated protein 20 kda; cyclin-dependent kinase inhibitor 1a protein; cdk interacting protein 1; cdk2 associated protein 20 kda; senescent cell-derived inhibitor protein 1; cdk-interacting protein 1; cdk2 inhibitor protein; cdkn1 protein; cdkn1a protein; senescent cell derived inhibitor protein 1; cyclin dependent kinase inhibitor 1a protein; p21 cell cycle regulator; p21 cyclin kinase inhibitor; cell cycle regulator p21; cyclin dependent kinase inhibitor p21;

Is substance : O;

Details

Origin ID

D050759;

UMLS CUI

C0288472;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Pharmacological action(s)
- protein kinase inhibitors [MeSH Descriptor]
Record concept(s)
- Cyclin-Dependent kinase inhibitor p21 [MeSH concept]
Related MeSH Supplementary Concept(s)
- CDKN1A protein, human [MeSH Supplementary Concept]
- Cdkn1a protein, mouse [MeSH Supplementary Concept]
- Cdkn1a protein, rat [MeSH Supplementary Concept]
- cdkn1a protein, zebrafish [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Cyclin-Dependent Kinase Inhibitor 1 [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients