NCIt synonyms : CBL-3; Cbl Proto-Oncogene C wt Allele; CBL-SL; RNF57; Cbl Proto-Oncogene, E3 Ubiquitin Protein Ligase C Gene; Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence C Gene; Cbl Proto-Oncogene C, E3 Ubiquitin Protein Ligase Gene; Cas-Br-M Murine Ecotropic Retroviral Transforming Sequence C Gene;
NCIt definition : Human CBLC wild-type allele is located in the vicinity of 19q13.2 and is approximately
23 kb in length. This allele, which encodes E3 ubiquitin-protein ligase CBL-C protein,
plays a role in the modulation of signal transduction. Mutation of the gene may be
associated with acute myeloid leukemia.;