NCIt synonyms : SMAD Family Member 3 wt Allele; JV15-2; MADH3; SMAD, Mothers Against DPP Homolog 3 (Drosophila) Gene; LDS3; HSPC193; MADH3 wt Allele; LDS1C; Mothers Against Decapentaplegic, Drosophila, Homolog of, 3 Gene; MAD, Mothers Against Decapentaplegic Homolog 3 Gene; MAD, Mothers Against Decapentaplegic Homolog 3 (Drosophila) Gene; HsT17436;
NCIt definition : Human SMAD3 wild-type allele is located in the vicinity of 15q22.33 and is approximately
130 kb in length. This allele, which encodes mothers against decapentaplegic homolog
3 protein, plays a role in the transcriptional regulation of the cellular response
to transforming growth factor-beta.;