t(11;14)(q13;q32)

Preferred Label : t(11;14)(q13;q32);

NCIt synonyms : t 11 14 q13 q32;

NCIt definition : A cytogenetic abnormality that refers to the translocation of the long arm (q13) of chromosome 11 and the long arm (q32) of chromosome 14. It results in up-regulation of cyclin D1 and is the most common translocation detected in multiple myeloma.;

Details

Origin ID

C27490;

UMLS CUI

C1515705;

Molecular abnormality of diseases
- IgM Monoclonal Gammopathy of Undetermined Significance, Plasma Cell Type [NCIt concept]
Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
cytogenetic_abnormality_involves_chromosome
- Human Chromosome 11 [NCIt concept]
- Human Chromosome 14 [NCIt concept]
is_abnormality_of_gene
- CCND1/IGH Fusion Gene [NCIt concept]
- CCND1/IGHG1 Fusion Gene [NCIt concept]
is_cytogenetic_abnormality_of_disease
- Cyclin D1-Positive Mantle Cell Lymphoma [NCIt concept]
- Multiple Myeloma with t(11;14)(q13;q32) [NCIt concept]
may_be_cytogenetic_abnormality_of_disease
- Ann Arbor Stage I Mantle Cell Lymphoma [NCIt concept]
- Ann Arbor Stage II Contiguous Mantle Cell Lymphoma [NCIt concept]
- Ann Arbor Stage II Mantle Cell Lymphoma [NCIt concept]
- Ann Arbor Stage II Non-Contiguous Mantle Cell Lymphoma [NCIt concept]
- Ann Arbor Stage III Mantle Cell Lymphoma [NCIt concept]
- Ann Arbor Stage IV Mantle Cell Lymphoma [NCIt concept]
- B-Cell Prolymphocytic Leukemia [NCIt concept]
- Blastoid Variant Mantle Cell Lymphoma [NCIt concept]
- Colon Mantle Cell Lymphoma [NCIt concept]
- Colorectal Mantle Cell Lymphoma [NCIt concept]
- Cutaneous Mantle Cell Lymphoma [NCIt concept]
- DS Stage I Multiple Myeloma [NCIt concept]
- DS Stage IA Multiple Myeloma [NCIt concept]
- DS Stage IB Multiple Myeloma [NCIt concept]
- DS Stage II Multiple Myeloma [NCIt concept]
- DS Stage IIA Multiple Myeloma [NCIt concept]
- DS Stage IIB Multiple Myeloma [NCIt concept]
- DS Stage III Multiple Myeloma [NCIt concept]
- DS Stage IIIA Multiple Myeloma [NCIt concept]
- DS Stage IIIB Multiple Myeloma [NCIt concept]
- Gastric Mantle Cell Lymphoma [NCIt concept]
- ISS Stage I Multiple Myeloma [NCIt concept]
- ISS Stage II Multiple Myeloma [NCIt concept]
- ISS Stage III Multiple Myeloma [NCIt concept]
- Indolent Multiple Myeloma [NCIt concept]
- Mantle Cell Lymphoma by Ann Arbor Stage [NCIt concept]
- Multiple Myeloma [NCIt concept]
- Multiple Myeloma Myeloma by DS Stage [NCIt concept]
- Multiple Myeloma Post-Transplant Lymphoproliferative Disorder [NCIt concept]
- Multiple Myeloma by ISS Stage [NCIt concept]
- Multiple Myeloma by RISS Stage [NCIt concept]
- Non-Secretory Multiple Myeloma [NCIt concept]
- Osteosclerotic Multiple Myeloma [NCIt concept]
- Pleomorphic Variant Mantle Cell Lymphoma [NCIt concept]
- RISS Stage I Multiple Myeloma [NCIt concept]
- RISS Stage II Multiple Myeloma [NCIt concept]
- RISS Stage III Multiple Myeloma [NCIt concept]
- Recurrent B-Cell Prolymphocytic Leukemia [NCIt concept]
- Recurrent Mantle Cell Lymphoma [NCIt concept]
- Recurrent Multiple Myeloma [NCIt concept]
- Refractory B-Cell Prolymphocytic Leukemia [NCIt concept]
- Refractory Mantle Cell Lymphoma [NCIt concept]
- Refractory Multiple Myeloma [NCIt concept]
- Small Intestinal Mantle Cell Lymphoma [NCIt concept]
- Smoldering Multiple Myeloma [NCIt concept]
- Splenic Manifestation of B-Cell Prolymphocytic Leukemia [NCIt concept]
- Splenic Mantle Cell Lymphoma [NCIt concept]
- Triple-Class Refractory Multiple Myeloma [NCIt concept]
molecular_abnormality_involves_gene
- CCND1 Gene [NCIt concept]
- IGH Locus Fusion Gene [NCIt concept]
- Immunoglobulin Heavy Locus [NCIt concept]

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