NCIt related terms : Prolymphocytic leukemia, B-cell type;
NCIt definition : A malignant B-cell lymphoproliferative process affecting the blood, bone marrow, and
spleen. The B-prolymphocytes are medium-sized, round lymphoid cells with prominent
nucleoli. The B-prolymphocytes must exceed 55% of lymphoid cells in the blood. Cases
of transformed chronic lymphocytic leukemia (CLL) and CLL with increased prolymphocytes
are excluded. The prognosis is poor. (WHO, 2001);