IgM Monoclonal Gammopathy of Undetermined Significance, Plasma Cell Type

Preferred Label : IgM Monoclonal Gammopathy of Undetermined Significance, Plasma Cell Type;

NCIt synonyms : IgM MGUS, Plasma Cell Type;

NCIt definition : A subtype of IgM monoclonal gammopathy of undetermined significance characterized by the presence of clonal plasma cells, absence of clonal B-lymphocytes, and absence of MYD88 gene mutation. The t(11;14)(q13;q32) is present in some cases. This subtype is considered a precursor of multiple myeloma.;

Neoplastic status : Precancerous;

NCI Metathesaurus CUI : CL1906757;

Détails

Origin ID

C199382;

UMLS CUI

C5855556;

Disease excludes abnormal cell
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Has associated anatomic sites
- Hematopoietic System [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Aberrant Clonal Plasma Cell Population [NCIt concept]
- Constitutional Symptom [NCIt concept]
- Hepatosplenomegaly [NCIt concept]
- Lymphadenopathy [NCIt concept]
disease_excludes_molecular_abnormality
- MYD88 Gene Mutation [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic Plasma Cell [NCIt concept]
disease_has_finding
- Bone Marrow Lymphoplasmacytic Infiltration of Less than 10% [NCIt concept]
- Monoclonal Gammopathy [NCIt concept]
- Serum IgM Monoclonal Gammopathy of Less than 30g/L [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_may_have_molecular_abnormality
- t(11;14)(q13;q32) [NCIt concept]

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