Multiple Myeloma with t(11;14)(q13;q32)

Preferred Label : Multiple Myeloma with t(11;14)(q13;q32);

NCIt synonyms : Plasma Cell Myeloma with t(11;14)(q13;q32);

NCIt definition : Multiple myeloma characterized by the presence of t(11;14)(q13;q32). It is the most common immunoglobulin heavy chain translocation found in multiple myeloma and results in CCND1 overexpression.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1906787;

Details

Origin ID

C199413;

UMLS CUI

C5855579;

Disease excludes abnormal cell
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Has associated anatomic sites
- Hematopoietic System [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
Has cytogenetic abnormalities
- CCND Family Gene Translocation [NCIt concept]
- t(11;14)(q13;q32) [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Localized Lesion [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic Plasma Cell [NCIt concept]
disease_has_finding
- Aberrant Clonal Plasma Cell Population [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Neoplastic Plasma Cells Present in Bone Marrow [NCIt concept]
- Recurrent Genetic Abnormalities Present [NCIt concept]
disease_has_molecular_abnormality
- CCND1 Protein Overexpression [NCIt concept]
- Clonal Immunoglobulin Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Bone Marrow-Homing Plasma Cell [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
- Plasma Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]

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