NCIt synonyms : Stage II Multiple Myeloma; Durie/Salmon Stage II Plasma Cell Myeloma; Stage II Plasma Cell Myeloma; Durie/Salmon Stage II Multiple Myeloma; DS Stage II Plasma Cell Myeloma; Multiple Myeloma Stage II;
NCIt related terms : DS Stage II Multiple Myeloma/Plasma Cell Myeloma;
NCIt definition : Multiple myeloma that fits in neither stage I nor stage III. Estimated myeloma cell
mass: 0.6 to 1.2 trillion (1012)/m2 (intermediate burden). The following subclassification
of stages is used: a. Creatinine less than 2.0 mg/dL, b. Creatinine greater than or
equal to 2.0 mg/dL. Impaired renal function worsens prognosis regardless of stage.
Note that the newer International Staging System defines stage II quite differently:
Beta-2-microglobulin less than 3.5 and albumin less than 3.5 or beta-2-microglobulin
3.5 to less than 5.5 (median survival of 44 months). (PDQ);
Alternative definition : NCI-GLOSS: Cancer in which a moderate number of cancer cells have spread throughout
the body.;