Refractory Systemic Anaplastic Large Cell Lymphoma, ALK-Positive

Preferred Label : Refractory Systemic Anaplastic Large Cell Lymphoma, ALK-Positive;

NCIt synonyms : Refractory Primary Systemic Anaplastic Large Cell Lymphoma, ALK-Positive;

NCIt definition : Systemic anaplastic large cell lymphoma, ALK-positive that is resistant to treatment.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL1663589;

Details

Origin ID

C181048;

UMLS CUI

C5556809;

Disease excludes abnormal cell
- Neoplastic B-Lymphocyte [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor Natural Killer Cell [NCIt concept]
- Precursor T-Lymphoblast [NCIt concept]
Disease may have findings
- Extranodal Disease [NCIt concept]
- Favorable Clinical Outcome [NCIt concept]
- Lymphadenopathy [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Anaplastic Large T-Lymphocyte [NCIt concept]
- Hallmark Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
disease_has_finding
- Anaplastic Lesion [NCIt concept]
- CD30-Positive Neoplastic Cells Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Primary Lesion [NCIt concept]
- Refractory Disease [NCIt concept]
- Systemic Disease [NCIt concept]
disease_has_molecular_abnormality
- ALK Fusion Protein Expression [NCIt concept]
- Rearrangement of 2p23 [NCIt concept]
disease_has_normal_cell_origin
- Activated Mature Cytotoxic T-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature T-Lymphocyte [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte and Natural Killer Cell [NCIt concept]
- T-Lymphocyte and Natural Killer Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_mapped_to_gene
- ALK Gene [NCIt concept]
- ATIC/ALK Fusion Gene [NCIt concept]
- CLTC/ALK Fusion Gene [NCIt concept]
- MSN/ALK Fusion Gene [NCIt concept]
- NPM1/ALK Fusion Gene [NCIt concept]
- RNF213/ALK Fusion Gene [NCIt concept]
- TFG/ALK Fusion Gene [NCIt concept]
- TPM3/ALK Fusion Gene [NCIt concept]
- TPM4/ALK Fusion Gene [NCIt concept]
disease_may_have_abnormal_cell
- Doughnut Cell [NCIt concept]
- Hodgkin-Like Cell [NCIt concept]
- Reed-Sternberg-Like Cell [NCIt concept]
disease_may_have_cytogenetic_abnormality
- inv(2)(p23;q35) [NCIt concept]
- t(1;2)(q25;p23) [NCIt concept]
- t(2;17)(p23;q23) [NCIt concept]
- t(2;17)(p23;q35) [NCIt concept]
- t(2;19)(p23;p13) [NCIt concept]
- t(2;22)(p23;q11) [NCIt concept]
- t(2;3)(p23;q21) [NCIt concept]
- t(2;5)(p23;q35) [NCIt concept]
- t(X;2)(q11-12;p23) [NCIt concept]
disease_may_have_molecular_abnormality
- ALO17-ALK Fusion Protein Expression [NCIt concept]
- ATIC-ALK Fusion Protein Expression [NCIt concept]
- CLTC-ALK Fusion Protein Expression [NCIt concept]
- Clonal T-Cell Receptor Beta Chain Gene Rearrangement [NCIt concept]
- Clonal T-Cell Receptor Gamma Chain Gene Rearrangement [NCIt concept]
- MSN-ALK Fusion Protein Expression [NCIt concept]
- MYH9-ALK Fusion Protein Expression [NCIt concept]
- NPM-ALK Fusion Protein Expression [NCIt concept]
- TFG-ALK Fusion Protein Expression [NCIt concept]
- TPM3-ALK Fusion Protein Expression [NCIt concept]
- TPM4-ALK Fusion Protein Expression [NCIt concept]

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