MSN/ALK Fusion Gene

Preferred Label : MSN/ALK Fusion Gene;

NCIt synonyms : MSN-ALK Fusion Gene; MSN::ALK Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(X;2)(q11;p23) which fuses most of the coding sequence of the MSN gene with the 3' portion of the ALK gene. This rearrangement is associated with rare cases of anaplastic large cell lymphoma.;

Details

Origin ID

C101059;

UMLS CUI

C3639968;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_encodes_gene_product
- MSN/ALK Fusion Protein [NCIt concept]
gene_involved_in_molecular_abnormality
- MSN-ALK Fusion Protein Expression [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
gene_mapped_to_disease
- Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Central Nervous System Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Childhood Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Recurrent Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Refractory Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
gene_plays_role_in_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- ALK Gene [NCIt concept]
- MSN Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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