Anaplastic Large Cell Lymphoma, ALK-Positive

Preferred Label : Anaplastic Large Cell Lymphoma, ALK-Positive;

NCIt synonyms : ALK-Positive Anaplastic Large Cell Lymphoma; ALKoma; ALCL, ALK ;

NCIt related terms : Anaplastic large cell lymphoma, ALK positive; Anaplastic large cell lymphoma, ALK-positive, unspecified site;

NCIt definition : A T-cell peripheral lymphoma composed of usually large, pleomorphic, CD30 positive T-lymphocytes with abundant cytoplasm. It is characterized by the presence of a translocation involving the ALK gene and expression of ALK fusion protein. Most patients present with peripheral and/or abdominal lymphadenopathy, and often have advanced disease and extranodal involvement.;

Neoplastic status : Malignant;

ICD-O code : 9714/3;

Codes from synonyms : C84.60;

Details

Origin ID

C37193;

UMLS CUI

C1332079;

Automatic exact mappings (from CISMeF team)
- ALK-negative anaplastic large cell lymphoma [ORDO Disease]
- Anaplastic large cell lymphoma, ALK positive [ICD-11 More detail]
- Anaplastic large cell lymphoma, ALK-positive [ICD-11 Subcategory]
Currated CISMeF NLP mapping
- ALK positive anaplastic large cell lymphoma [Disease (Nov.)]
- ALK-positive anaplastic large cell lymphoma [ORDO Disease]
- Anaplastic large cell lymphoma, ALK-positive [ICD-10 Sub-category]
Disease excludes abnormal cell
- Neoplastic B-Lymphocyte [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor Natural Killer Cell [NCIt concept]
- Precursor T-Lymphoblast [NCIt concept]
Disease may have findings
- Extranodal Disease [NCIt concept]
- Favorable Clinical Outcome [NCIt concept]
- Lymphadenopathy [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
UMLS correspondences (same concept)
- ALK positive anaplastic large cell lymphoma [Disease (Nov.)]
- ALK-positive anaplastic large cell lymphoma [ORDO Disease]
- Anaplastic large cell lymphoma, ALK-positive [ICD-10 Sub-category]
concept_is_in_subset
- CPTAC Codelists Terminology [NCIt concept]
- CPTAC Neoplasms Codelist [NCIt concept]
- CPTAC Terminology [NCIt concept]
- Cellosaurus Disease Terminology [NCIt concept]
- Cellosaurus Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCIt Neoplasm Core Terminology [NCIt concept]
- mCode Cancer Disorder Value Set [NCIt concept]
- mCode Elixhauser Lymphoma Value Set [NCIt concept]
- mCode Primary Cancer Disorder Value Set [NCIt concept]
- mCode Primary Malignant Neoplasm Disorder Value Set [NCIt concept]
- mCode Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Anaplastic Large T-Lymphocyte [NCIt concept]
- Hallmark Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
disease_has_finding
- Anaplastic Lesion [NCIt concept]
- CD30-Positive Neoplastic Cells Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_molecular_abnormality
- ALK Fusion Protein Expression [NCIt concept]
- Rearrangement of 2p23 [NCIt concept]
disease_has_normal_cell_origin
- Activated Mature Cytotoxic T-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature T-Lymphocyte [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte and Natural Killer Cell [NCIt concept]
- T-Lymphocyte and Natural Killer Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_mapped_to_gene
- ALK Gene [NCIt concept]
- ATIC/ALK Fusion Gene [NCIt concept]
- CLTC/ALK Fusion Gene [NCIt concept]
- MSN/ALK Fusion Gene [NCIt concept]
- NPM1/ALK Fusion Gene [NCIt concept]
- RNF213/ALK Fusion Gene [NCIt concept]
- TFG/ALK Fusion Gene [NCIt concept]
- TPM3/ALK Fusion Gene [NCIt concept]
- TPM4/ALK Fusion Gene [NCIt concept]
disease_may_have_abnormal_cell
- Doughnut Cell [NCIt concept]
- Hodgkin-Like Cell [NCIt concept]
- Reed-Sternberg-Like Cell [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal T-Cell Receptor Beta Chain Gene Rearrangement [NCIt concept]
- Clonal T-Cell Receptor Gamma Chain Gene Rearrangement [NCIt concept]
pathogenesis_of_disease_involves_gene
- ALK Gene [NCIt concept]
- ALK wt Allele [NCIt concept]
- ALKATI Allele [NCIt concept]
- ATIC/ALK Fusion Gene [NCIt concept]
- CLTC/ALK Fusion Gene [NCIt concept]
- MSN/ALK Fusion Gene [NCIt concept]
- NPM1/ALK Fusion Gene [NCIt concept]
- RNF213/ALK Fusion Gene [NCIt concept]
- TFG/ALK Extra Long Form Fusion Gene [NCIt concept]
- TFG/ALK Fusion Gene [NCIt concept]
- TFG/ALK Long Form Fusion Gene [NCIt concept]
- TFG/ALK Short Form Fusion Gene [NCIt concept]
- TPM3/ALK Fusion Gene [NCIt concept]
- TPM4/ALK Fusion Gene [NCIt concept]

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