RNF213/ALK Fusion Gene

Preferred Label : RNF213/ALK Fusion Gene;

NCIt synonyms : ALK/ALO17 Fusion Gene; ALO17-ALK Fusion Gene; RNF213-ALK Fusion Gene; ALO17/ALK Fusion Gene; ALK/RNF213 Fusion Gene; RNF213::ALK Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(2;17)(p23;q25) which fuses the first 16 exons of the RNF213 gene with the last ten exons of the ALK gene. This fusion is associated with anaplastic large cell lymphoma.;

Details

Origin ID

C99869;

UMLS CUI

C3151472;

Automatic exact mappings (from CISMeF team)
- Anaplastic lymphoma kinase [OMIM gene]
- Ring finger protein 213 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- RNF213/ALK Fusion Protein [NCIt concept]
gene_involved_in_molecular_abnormality
- ALO17-ALK Fusion Protein Expression [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
gene_mapped_to_disease
- Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Central Nervous System Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Childhood Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Recurrent Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Refractory Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
gene_plays_role_in_process
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- ALK Gene [NCIt concept]
- RNF213 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients