RNF213-ALK Fusion Protein Expression

Preferred Label : RNF213-ALK Fusion Protein Expression;

NCIt synonyms : ALO17-ALK Fusion Protein Expression; RNF213/ALK Fusion Protein Expression;

NCIt definition : A molecular abnormality characterized by the expression of a fusion protein that results from chromosomal recombination involving the human genes RNF213 and ALK. This abnormal protein is associated with ALK-positive anaplastic large cell lymphoma.;

Details

Origin ID

C45443;

UMLS CUI

C1706659;

Molecular abnormality of diseases
- Childhood Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Primary Central Nervous System Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Recurrent Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Refractory Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
molecular_abnormality_involves_gene
- ALK Gene [NCIt concept]
- RNF213 Gene [NCIt concept]
- RNF213/ALK Fusion Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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