TFG/ALK Fusion Gene

Preferred Label : TFG/ALK Fusion Gene;

NCIt synonyms : TFG-ALK; TFG::ALK Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(2;3)(p23;q21) which fuses a portion of the 5' part of the TFG gene to the last 10 exons of the ALK gene. This rearrangement is associated with anaplastic large cell lymphoma.;

Details

Origin ID

C101075;

UMLS CUI

C3537318;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_encodes_gene_product
- TFG/ALK Extra Long Form Fusion Protein [NCIt concept]
- TFG/ALK Fusion Protein [NCIt concept]
- TFG/ALK Long Form Fusion Protein [NCIt concept]
- TFG/ALK Short Form Fusion Protein [NCIt concept]
gene_involved_in_molecular_abnormality
- TFG-ALK Fusion Protein Expression [NCIt concept]
- TFG-ALKlong Fusion Protein Expression [NCIt concept]
- TFG-ALKshort Fusion Protein Expression [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
gene_mapped_to_disease
- Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Central Nervous System Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Childhood Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Recurrent Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Refractory Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
gene_plays_role_in_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- ALK Gene [NCIt concept]
- TFG Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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