TFG/ALK Extra Long Form Fusion Protein

Preferred Label : TFG/ALK Extra Long Form Fusion Protein;

NCIt synonyms : TRK-Fused Gene/Anaplastic Large Cell Lymphoma Kinase Extra Long Form Fusion Protein; TFG-ALK(XL); TFG-ALK XL; Protein TFG/ALK Tyrosine Kinase Receptor Extra Long Form Fusion Protein; TFG::ALK Extra Long Form Fusion Protein;

NCIt definition : A fusion protein (803 aa, 89 kDa) encoded by the TFG/ALK extra long form fusion gene. This protein is comprised of the N-terminal half of protein TFG, including the coiled-coil oligomerization domain, fused to the cytoplasmic domain of the ALK tyrosine kinase receptor protein.;

NCIt note : The TGF/ALK extra long form fusion protein is a constitutively dimerized and activated tyrosine kinase.;

Details

Origin ID

C101082;

UMLS CUI

C3537365;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Fusion Gene [NCIt concept]
- TFG/ALK Extra Long Form Fusion Gene [NCIt concept]
- TFG/ALK Fusion Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- ALK Gene [NCIt concept]
- TFG Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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