TFG/ALK Short Form Fusion Protein

Preferred Label : TFG/ALK Short Form Fusion Protein;

NCIt synonyms : Protein TFG/ALK Tyrosine Kinase Receptor Short Form Fusion Protein; TFG-ALK(S); TRK-Fused Gene/Anaplastic Lymphoma Kinase (Ki-1) Short Form Fusion Protein; TFG::ALK Short Form Fusion Protein;

NCIt definition : A fusion protein (701 aa, 78 kDa) encoded by the TFG/ALK short form fusion gene. This protein is comprised of about one third of the N-terminal sequence of protein TFG, including the coiled-coil oligomerization domain, fused to the cytoplasmic domain of the ALK tyrosine kinase receptor protein.;

NCIt note : The TGF/ALK short form fusion protein is a constitutively dimerized and activated tyrosine kinase.;

Détails

Origin ID

C101080;

UMLS CUI

C3537361;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- ALK Fusion Gene [NCIt concept]
- Fusion Gene [NCIt concept]
- TFG/ALK Fusion Gene [NCIt concept]
- TFG/ALK Short Form Fusion Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- ALK Gene [NCIt concept]
- TFG Gene [NCIt concept]

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