Preferred Label : TFG/ALK Short Form Fusion Protein;
NCIt synonyms : Protein TFG/ALK Tyrosine Kinase Receptor Short Form Fusion Protein; TFG-ALK(S); TRK-Fused Gene/Anaplastic Lymphoma Kinase (Ki-1) Short Form Fusion Protein; TFG::ALK Short Form Fusion Protein;
NCIt definition : A fusion protein (701 aa, 78 kDa) encoded by the TFG/ALK short form fusion gene.
This protein is comprised of about one third of the N-terminal sequence of protein
TFG, including the coiled-coil oligomerization domain, fused to the cytoplasmic domain
of the ALK tyrosine kinase receptor protein.;
NCIt note : The TGF/ALK short form fusion protein is a constitutively dimerized and activated
tyrosine kinase.;