CLTC/ALK Fusion Gene

Preferred Label : CLTC/ALK Fusion Gene;

NCIt synonyms : ALK/CLTC Fusion Gene; CLTC-ALK Fusion Gene; CLTC::ALK Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal translocation t(2;17)(p23;q23) which fuses the first 31 exons of the CLTC gene with the last ten exons of the ALK gene. This fusion is associated with both anaplastic large cell lymphoma and inflammatory myofibroblastic tumors.;

Details

Origin ID

C99873;

UMLS CUI

C3151474;

Automatic exact mappings (from CISMeF team)
- Anaplastic lymphoma kinase [OMIM gene]
- Clathrin, heavy polypeptide [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CLTC/ALK Fusion Protein [NCIt concept]
gene_involved_in_molecular_abnormality
- CLTC-ALK Fusion Protein Expression [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Inflammatory Myofibroblastic Tumor [NCIt concept]
gene_mapped_to_disease
- Abdominal Inflammatory Myofibroblastic Tumor [NCIt concept]
- Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Bladder Inflammatory Myofibroblastic Tumor [NCIt concept]
- Breast Inflammatory Myofibroblastic Tumor [NCIt concept]
- Cardiac Inflammatory Myofibroblastic Tumor [NCIt concept]
- Central Nervous System Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Central Nervous System Inflammatory Myofibroblastic Tumor [NCIt concept]
- Childhood Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Childhood Inflammatory Myofibroblastic Tumor [NCIt concept]
- Digestive System Inflammatory Myofibroblastic Tumor [NCIt concept]
- Gastric Inflammatory Myofibroblastic Tumor [NCIt concept]
- Head and Neck Inflammatory Myofibroblastic Tumor [NCIt concept]
- Inflammatory Myofibroblastic Tumor [NCIt concept]
- Laryngeal Inflammatory Myofibroblastic Tumor [NCIt concept]
- Liver Inflammatory Myofibroblastic Tumor [NCIt concept]
- Lung Inflammatory Myofibroblastic Tumor [NCIt concept]
- Prostate Inflammatory Myofibroblastic Tumor [NCIt concept]
- Recurrent Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Refractory Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Retroperitoneal Inflammatory Myofibroblastic Tumor [NCIt concept]
- Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Uterine Corpus Inflammatory Myofibroblastic Tumor [NCIt concept]
gene_plays_role_in_process
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- ALK Gene [NCIt concept]
- CLTC Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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