CLTC/ALK Fusion Protein

Preferred Label : CLTC/ALK Fusion Protein;

NCIt synonyms : Clathrin Heavy Chain 1/ALK Tyrosine Kinase Receptor Fusion Protein; CLTC-ALK Fusion Protein; CLTC::ALK Fusion Protein;

NCIt definition : A fusion protein that is encoded by the CLTC/ALK fusion gene. This protein contains most of the clathrin heavy chain 1 protein including the trimerization domain and the cytoplasmic domain of the ALK tyrosine kinase receptor protein.;

NCIt note : The CLTC/ALK fusion protein is a constitutively dimerized and activated tyrosine kinase.;

Details

Origin ID

C99874;

UMLS CUI

C3275011;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CLTC/ALK Fusion Gene [NCIt concept]
- Fusion Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Signal Transduction [NCIt concept]
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- ALK Gene [NCIt concept]
- CLTC Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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