CLTC-ALK Fusion Protein Expression

Preferred Label : CLTC-ALK Fusion Protein Expression;

NCIt definition : A molecular abnormality characterized by the expression of a fusion protein that results from chromosomal recombination involving the human genes CLTC and ALK. This abnormal protein is associated with ALK-positive anaplastic large cell lymphoma and inflammatory myofibroblastic tumors.;

Details

Origin ID

C37216;

UMLS CUI

C1511444;

Molecular abnormality of diseases
- Abdominal Inflammatory Myofibroblastic Tumor [NCIt concept]
- Bladder Inflammatory Myofibroblastic Tumor [NCIt concept]
- Breast Inflammatory Myofibroblastic Tumor [NCIt concept]
- Cardiac Inflammatory Myofibroblastic Tumor [NCIt concept]
- Central Nervous System Inflammatory Myofibroblastic Tumor [NCIt concept]
- Childhood Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Childhood Inflammatory Myofibroblastic Tumor [NCIt concept]
- Digestive System Inflammatory Myofibroblastic Tumor [NCIt concept]
- Gastric Inflammatory Myofibroblastic Tumor [NCIt concept]
- Head and Neck Inflammatory Myofibroblastic Tumor [NCIt concept]
- Laryngeal Inflammatory Myofibroblastic Tumor [NCIt concept]
- Liver Inflammatory Myofibroblastic Tumor [NCIt concept]
- Lung Inflammatory Myofibroblastic Tumor [NCIt concept]
- Orbital Inflammatory Myofibroblastic Tumor [NCIt concept]
- Primary Central Nervous System Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Prostate Inflammatory Myofibroblastic Tumor [NCIt concept]
- Recurrent Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Refractory Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Retroperitoneal Inflammatory Myofibroblastic Tumor [NCIt concept]
- Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Uterine Corpus Inflammatory Myofibroblastic Tumor [NCIt concept]
Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
molecular_abnormality_involves_gene
- ALK Gene [NCIt concept]
- CLTC Gene [NCIt concept]
- CLTC/ALK Fusion Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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