ATIC/ALK Fusion Gene

Preferred Label : ATIC/ALK Fusion Gene;

NCIt synonyms : ATIC-ALK Fusion Gene; ATIC::ALK Fusion Gene;

NCIt definition : A fusion gene that results from a chromosomal inversion inv(2)(p23q35) which fuses the first 7 exons of the ATIC gene with exon 20 of the ALK gene. This rearrangement is associated with rare cases of anaplastic large cell lymphoma.;

Details

Origin ID

C101046;

UMLS CUI

C3639959;

Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_encodes_gene_product
- ATIC/ALK Fusion Protein [NCIt concept]
gene_involved_in_molecular_abnormality
- ATIC-ALK Fusion Protein Expression [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
gene_mapped_to_disease
- Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Central Nervous System Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Childhood Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Recurrent Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Refractory Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
related_to_genetic_biomarker
- ALK Gene [NCIt concept]
- ATIC Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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