Preferred Label : ATIC/ALK Fusion Protein;
NCIt synonyms : Bifunctional Purine Biosynthesis Protein PURH/ALK Tyrosine Kinase Receptor Fusion
Protein; ATIC-ALK Fusion Protein; ATIC::ALK Fusion Protein; Bifunctional Purine Biosynthesis Protein PURH::ALK Tyrosine Kinase Receptor Fusion
Protein;
NCIt definition : A fusion protein encoded by the ATIC/ALK fusion gene. This protein is comprised of
the IMPCH and the dimerization domains of the bifunctional purine biosynthesis protein
PURH fused to the cytoplasmic domain of the ALK tyrosine kinase receptor protein,
including the tyrosine kinase domain.;
NCIt note : The ATIC/ALK fusion protein is hypothesized to be a constitutively dimerized and activated
tyrosine kinase.;
Origin ID : C101047;
UMLS CUI : C3639960;
Semantic type(s)
- gene_encodes_gene_product
- related_to_genetic_biomarker
