MSN/ALK Fusion Protein

Preferred Label : MSN/ALK Fusion Protein;

NCIt synonyms : MSN-ALK Fusion Protein; Moesin/ALK Tyrosine Kinase Receptor Fusion Protein; MSN::ALK Fusion Protein;

NCIt definition : A fusion protein encoded by the MSN/ALK fusion gene. This protein is comprised of most of the moesin protein, including the band 4.1 region, fused to the cytoplasmic domain of the ALK tyrosine kinase receptor protein, including the tyrosine kinase domain.;

NCIt note : The MSN/ALK fusion protein is hypothesized to be a constitutively dimerized and activated tyrosine kinase. MSN/ALK is localized at the plasma membrane.;

Details

Origin ID

C101060;

UMLS CUI

C3639969;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Fusion Gene [NCIt concept]
- MSN/ALK Fusion Gene [NCIt concept]
gene_product_plays_role_in_biological_process
- Tyrosine Phosphorylation [NCIt concept]
related_to_genetic_biomarker
- ALK Gene [NCIt concept]
- MSN Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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