t(2;5)(p23;q35)

Preferred Label : t(2;5)(p23;q35);

NCIt synonyms : t 2 5;

NCIt definition : A chromosomal translocation involving breakpoints within the p23 band on the short arm of chromosome 2 and the q35 band on the long arm of chromosome 5. This rearrangement is associated with NPM1-ALK or SQSTM1-ALK fusion gene expression and anaplastic large cell lymphoma.;

Détails

Origin ID

C27711;

UMLS CUI

C1515757;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
cytogenetic_abnormality_involves_chromosome
- Human Chromosome 2 [NCIt concept]
- Human Chromosome 5 [NCIt concept]
is_abnormality_of_gene
- NPM1/ALK Fusion Gene [NCIt concept]
may_be_cytogenetic_abnormality_of_disease
- Childhood Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Primary Central Nervous System Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Recurrent Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Refractory Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
- Systemic Anaplastic Large Cell Lymphoma, ALK-Positive [NCIt concept]
molecular_abnormality_involves_gene
- ALK Gene [NCIt concept]
- Receptor Tyrosine Kinase Gene [NCIt concept]
related_to_genetic_biomarker
- NPM1/ALK Fusion Gene [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

Vous pouvez consulter :

recommendations
documents concerning education
documents for patients