antibodies, bispecific

Preferred Label : antibodies, bispecific;

MeSH definition : Antibodies, often monoclonal, in which the two antigen-binding sites are specific for separate ANTIGENIC DETERMINANTS. They are artificial antibodies produced by chemical crosslinking, fusion of HYBRIDOMA cells, or by molecular genetic techniques. They function as the main mediators of targeted cellular cytotoxicity and have been shown to be efficient in the targeting of drugs, toxins, radiolabeled haptens, and effector cells to diseased tissue, primarily tumors.;

MeSH synonym : bispecific antibodies; bifunctional antibodies; antibodies, bifunctional;

Wikipedia automatic translation : Bispecific monoclonal antibody;

MeSH hyponym : bispecific monoclonal antibodies; Antibodies, Bispecific Monoclonal; Monoclonal Antibodies, Bispecific;

MeSH annotation : do not coordinate with ANTIBODY FORMATION for /biosynthesis;

Wikipedia link : https://en.wikipedia.org/wiki/Bispecific monoclonal antibody;

Is substance : O;

Details

Origin ID

D018033;

UMLS CUI

C0206492;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Bispecific Antibody [NCIt concept]
Indexing information
- ertumaxomab [MeSH Supplementary Concept]
Pharmacological action(s)
- immunologic factors [MeSH Descriptor]
Record concept(s)
- antibodies, bispecific [MeSH concept]
- bispecific monoclonal antibodies [MeSH concept]
Related MeSH Supplementary Concept(s)
- 2B1 monoclonal antibody [MeSH Supplementary Concept]
- 5.2-OKT3 bispecific single-chain antibody fragment [MeSH Supplementary Concept]
- ABBV-428 [MeSH Supplementary Concept]
- AFM13 [MeSH Supplementary Concept]
- AMG 330 [MeSH Supplementary Concept]
- BAT2022 [MeSH Supplementary Concept]
- Bi20 antibody [MeSH Supplementary Concept]
- CD20Bi antibody [MeSH Supplementary Concept]
- CV1206_521_GS [MeSH Supplementary Concept]
- Istiratumab [MeSH Supplementary Concept]
- JNJ-61178104 [MeSH Supplementary Concept]
- MDX-H210 antibody [MeSH Supplementary Concept]
- MM-111 [MeSH Supplementary Concept]
- OC-TR monoclonal antibody [MeSH Supplementary Concept]
- OKT3xAntag2 [MeSH Supplementary Concept]
- PF-06671008 [MeSH Supplementary Concept]
- Pasotuxizumab [MeSH Supplementary Concept]
- RBT-0813 [MeSH Supplementary Concept]
- Solitomab [MeSH Supplementary Concept]
- amivantamab [MeSH Supplementary Concept]
- antibody MDXH447 [MeSH Supplementary Concept]
- bispecific antibody ERY974 [MeSH Supplementary Concept]
- blinatumomab [MeSH Supplementary Concept]
- catumaxomab [MeSH Supplementary Concept]
- cibisatamab [MeSH Supplementary Concept]
- emicizumab [MeSH Supplementary Concept]
- faricimab [MeSH Supplementary Concept]
- glofitamab [MeSH Supplementary Concept]
- gremubamab [MeSH Supplementary Concept]
- navicixizumab [MeSH Supplementary Concept]
- zanidatamab [MeSH Supplementary Concept]
- zenocutuzumab [MeSH Supplementary Concept]
See also
- antibody specificity [MeSH Descriptor]
- cytotoxicity, immunologic [MeSH Descriptor]
- immunotoxins [MeSH Descriptor]
- radioimmunotherapy [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Bispecific Antibody [NCIt concept]
Validated automatic mappings to BTNT
- Bispecific Monoclonal Antibody [NCIt concept]

Keyword's position in hierarchy(ies) :

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