Cytokine Release Syndrome

Preferred Label : Cytokine Release Syndrome;

NCIt definition : A syndrome that occurs after therapeutic infusion of antibodies into the blood and is characterized by nausea, headache, tachycardia, hypotension, rash, and shortness of breath. It is caused by the release of cytokines from the cells that are targeted by the antibodies. Most patients experience a mild to moderate reaction; however, the reaction may be severe and life-threatening.;

Alternative definition : CTCAE: A disorder characterized by nausea, headache, tachycardia, hypotension, rash, and shortness of breath; it is caused by the release of cytokines from the cells.; NICHD: A systemic inflammatory reaction caused by the release of an excessive amount of cytokines into the circulation by activated T-cells.;

Codes from synonyms : E11264;

Details

Origin ID

C78251;

UMLS CUI

C0948245;

Automatic exact mappings (from CISMeF team)
- Congenital rubella syndrome [ORDO Disease]
- Cytokine Release Syndrome [MeSH concept]
- Cytokine storm [MedDRA Preferred Term]
- Cytokine storm [HPO term]
- cytokine storm syndrome [COVID-19 Thesaurus concept]
- rubella syndrome, congenital [MeSH Descriptor]
Currated CISMeF NLP mapping
- Cytokine Release Syndrome [MeSH Descriptor]
- Cytokine release syndrome [MedDRA Preferred Term]
- Cytokine-associated toxicity (disorder) [SNOMED CT concept]
Manual BTNT mappings - CISMeF
- cytokine storm syndrome in COVID-19 [Indication]
Semantic type(s)
- Disease or Syndrome [UMLS semantic type]
UMLS correspondences (same concept)
- Cytokine Release Syndrome [MeSH Descriptor]
- Cytokine release syndrome [MedDRA Preferred Term]
- Cytokine-associated toxicity (disorder) [SNOMED CT concept]
concept_is_in_subset
- CTCAE Adverse Events Version 4.0 Terminology [NCIt concept]
- NICHD Terminology [NCIt concept]
- Pediatric Adverse Events Terminology [NCIt concept]
- Pediatric Adverse Events Terminology Mapped to MedDRA [NCIt concept]
- SeroNet Authorized Values [NCIt concept]
- SeroNet Study Descriptors [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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