NCIt definition : Any monoclonal antibody that targets two different antigens. A bispecific monoclonal
antibody is made up of two different monoclonal antibodies or antibody fragments and
contains two different antigen-binding sites.;
Alternative definition : NCI-GLOSS: An antibody that can bind to two different antigens at the same time. Bispecific
monoclonal antibodies are being studied in the imaging and treatment of cancer. They
are made in the laboratory.;