Preferred Label : stevens-johnson syndrome;

MeSH definition : Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.;

MeSH synonym : stevens johnson syndrome;

CISMeF synonym : Stevens-Johnson; stevens-johnson's syndrome;

Wikipedia automatic translation : Stevens–Johnson syndrome;

MeSH Hyperonym : Stevens-Johnson syndrome toxic epidermal necrolysis spectrum; Stevens Johnson Syndrome Toxic Epidermal Necrolysis Spectrum; Toxic Epidermal Necrolysis Stevens-Johnson Syndrome Spectrum; Toxic Epidermal Necrolysis Stevens Johnson Syndrome; Toxic Epidermal Necrolysis Stevens Johnson Syndrome Spectrum; Toxic Epidermal Necrolysis Stevens-Johnson Syndrome; Stevens Johnson Syndrome Toxic Epidermal Necrolysis; Stevens-Johnson Syndrome Toxic Epidermal Necrolysis;

MeSH hyponym : Drug-Induced stevens johnson syndrome; Mycoplasma-Induced Stevens-Johnson syndrome; Mycoplasma Induced Stevens Johnson Syndrome; Stevens-Johnson Syndrome, Mycoplasma-Induced; Syndrome, Mycoplasma-Induced Stevens-Johnson; Mycoplasma-Induced Stevens Johnson Syndrome; Drug Induced Stevens Johnson Syndrome; Drug-Induced Stevens-Johnson Syndrome; Drug-Induced Stevens-Johnson Syndromes; Stevens-Johnson Syndrome, Drug-Induced; Stevens-Johnson Syndromes, Drug-Induced;

Related MeSH term : epidermal necrolysis, toxic; Epidermal Necrolyses, Toxic; Necrolyses, Toxic Epidermal; Necrolysis, Toxic Epidermal; Toxic Epidermal Necrolyses; Toxic Epidermal Necrolysis; Scalded Skin Syndrome, Nonstaphylococcal; Lyell's Syndrome; Lyell Syndrome; Lyell's Syndromes; Syndrome, Lyell's; Syndromes, Lyell's; Nonstaphylococcal Scalded Skin Syndrome;

MeSH annotation : a sometimes fatal form of erythema multiforme;

Wikipedia link : https://en.wikipedia.org/wiki/Stevens–Johnson syndrome;

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Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.

Ezetrol (ezetimibe) and the Risks of Drug-Induced Liver Injury and Severe Cutaneous Adverse Reactions
https://recalls-rappels.canada.ca/fr/avis-rappel/ezetrol-ezetimibe-et-risques-lesions-hepatiques-origine-medicamenteuse-et-reactions
2024
false
false
false
Canada
French
English
pharmacovigilance note
Ezetimibe
Chemical and Drug Induced Liver Injury
Drug-Induced Liver Disease
drug hypersensitivity syndrome
stevens-johnson syndrome
epidermal necrolysis, toxic
Drug-Induced stevens johnson syndrome
canada
administration, oral
ezetimibe
anticholesteremic agents

---
https://ansm.sante.fr/informations-de-securite/adagrasib-risque-potentiel-deffets-indesirables-cutanes-severes
2024
false
false
false
France
French
pharmacovigilance note
risk
adagrasib
stevens-johnson syndrome
epidermal necrolysis, toxic
adagrasib
antineoplastic agents
Adagrasib Regimen

---
https://www.cbip.be/fr/articles/4075?folia=4050
2023
false
false
false
Belgium
French
journal article
administration, oral
ivermectin
ivermectin
antiparasitic agents
drug eruptions
epidermal necrolysis, toxic
stevens-johnson syndrome
pharmacovigilance note

---
https://ansm.sante.fr/actualites/cancer-de-la-vessie-des-mesures-pour-reduire-le-risque-de-graves-reactions-cutanees-associe-a-lenfortumab-vedotin-autorise-en-acces-precoce
2022
false
false
false
France
French
urinary bladder neoplasms
enfortumab vedotin
Metastatic Bladder Urothelial Carcinoma
Locally Advanced Bladder Urothelial Carcinoma
patients guideline
continuity of patient care
drug eruptions
stevens-johnson syndrome
epidermal necrolysis, toxic
pharmacovigilance note
drug monitoring
enfortumab vedotin

---
https://drees.solidarites-sante.gouv.fr/publications/etudes-et-resultats/en-2019-le-salaire-net-moyen-dans-la-fonction-publique
2021
France
journal article
wages
epidermal necrolysis, toxic
publications
temefos
salaries and fringe benefits
stevens-johnson syndrome

---
https://ansm.sante.fr/informations-de-securite/tecentriq-atezolizumab-risque-de-reactions-cutanees-severes
2021
false
false
false
France
French
pharmacovigilance note
atezolizumab
risk
stevens-johnson syndrome
epidermal necrolysis, toxic
drug hypersensitivity syndrome
atezolizumab
antineoplastic agents
antibodies, monoclonal

---
https://www.has-sante.fr/jcms/p_3216204/fr/merlin-net-dci-triple-chambre-application-mymerlinpulse-references-app1004/app1005
2020
France
health technology assessment
Applications
attention
defibrillator, nos
automatism
implantable defibrillator
telemedicine
Applications
triplets
electric countershock
infusion pumps, implantable
Applications
defibrillators, implantable
epidermal necrolysis, toxic
neurofibromin 2
automatism
stevens-johnson syndrome

---
https://www.has-sante.fr/jcms/p_3216170/fr/merlin-net-dci-simple-chambre-application-mymerlinpulse-references-app1004/app1005
2020
France
health technology assessment
defibrillator, nos
neurofibromin 2
defibrillators
robot
attention
electric countershock
automatism
infusion pumps, implantable
Applications
Applications
telemedicine
defibrillators, implantable
automatism
epidermal necrolysis, toxic
Applications
implant, nos
defibrillators
automatism
stevens-johnson syndrome

---
https://www.has-sante.fr/jcms/p_3216201/fr/merlin-net-dci-double-chambre-application-mymerlinpulse-references-app1004/app1005
2020
France
health technology assessment
electric countershock
double
Applications
defibrillators, implantable
telemedicine
infusion pumps, implantable
automatism
Applications
Applications
neurofibromin 2
defibrillators
defibrillator, nos
implant, nos
automatism
robot
epidermal necrolysis, toxic
attention
defibrillators
automatism
stevens-johnson syndrome

---
http://www.orpha.net/data/patho/Emg/Int/fr/NecrolyseEpidermiqueToxique_FR_fr_EMG_ORPHA537.pdf
2019
false
false
false
France
emergency treatment
severity of illness index
epidermal necrolysis, toxic
algorithms
epidermal necrolysis, toxic
transportation of patients
resource guides
guideline
emergencies
epidermal necrolysis, toxic
stevens-johnson syndrome
stevens-johnson syndrome
stevens-johnson syndrome
transportation of patients

---
https://drees.solidarites-sante.gouv.fr/etudes-et-statistiques/publications/etudes-et-resultats/article/en-2017-dans-la-fonction-publique-hospitaliere-le-salaire-net-moyen-augmente-de
2019
France
technical report
salaries and fringe benefits
epidermal necrolysis, toxic
wages
publications
stevens-johnson syndrome

---
https://www.medg.fr/necrolyse-epidermique-toxique-syndromes-de-stevens-johnson-et-lyell
2018
France
teaching material
scientific and technical information
epidermal necrolysis, toxic
stevens-johnson syndrome
epidermis

---
https://www.jle.com/fr/revues/met/e-docs/necrolyse_epidermique_toxique_une_meta_analyse_312025/article.phtml
2018
false
false
false
France
French
journal article
epidermal necrolysis, toxic
signs and symptoms
meta-analysis
stevens-johnson syndrome
epidermal necrolysis, toxic
stevens-johnson syndrome
stevens-johnson syndrome

---
https://www.has-sante.fr/portail/jcms/c_2786056/fr/merlin-net-systeme-de-telesurveillance-pour-dai-double-chambre
2017
false
false
false
France
French
health technology assessment
implantable defibrillator
telemedicine
defibrillator, nos
defibrillators, implantable
neurofibromin 2
infusion pumps, implantable
epidermal necrolysis, toxic
systemic
double
stevens-johnson syndrome

---
https://www.has-sante.fr/portail/jcms/c_2786059/fr/merlin-net-systeme-de-telesurveillance-pour-dai-triple-chambre
2017
false
false
false
France
French
health technology assessment
implantable defibrillator
defibrillator, nos
defibrillators, implantable
epidermal necrolysis, toxic
neurofibromin 2
systemic
triplets
telemedicine
infusion pumps, implantable
triple
stevens-johnson syndrome

---
https://www.has-sante.fr/portail/jcms/c_2786062/fr/merlin-net-systeme-de-telesurveillance-pour-dai-simple-chambre
2017
false
false
false
France
French
health technology assessment
defibrillator, nos
systemic
neurofibromin 2
telemedicine
simple
implantable defibrillator
epidermal necrolysis, toxic
defibrillators, implantable
infusion pumps, implantable
stevens-johnson syndrome

---
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=FR&Expert=36426
2017
false
false
false
France
French
scientific and technical information
stevens-johnson syndrome
stevens-johnson syndrome

---
ARANESP - Risk of Severe Skin Reactions: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
http://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2017/63198a-fra.php
2017
false
false
false
Canada
French
English
Darbepoetin alfa
pharmacovigilance note
darbepoetin alfa
stevens-johnson syndrome
Toxic Epidermal Necrolysis
hematinics
injections, subcutaneous
injections, intravenous
Drug-Induced stevens johnson syndrome
epidermal necrolysis, toxic
anemia

---
KEYTRUDA (pembrolizumab) - Risk of Severe Skin Reactions: Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
http://canadiensensante.gc.ca/recall-alert-rappel-avis/hc-sc/2017/62670a-fra.php
2017
false
false
false
Canada
French
English
pharmacovigilance note
pembrolizumab
pembrolizumab
infusions, intravenous
antineoplastic agents
stevens-johnson syndrome
epidermal necrolysis, toxic
guidelines for drug use
carcinoma, non-small-cell lung
melanoma
programmed cell death 1 receptor
Drug-Induced stevens johnson syndrome
antibodies, monoclonal
antibodies, monoclonal, humanized

---
http://www.has-sante.fr/portail/jcms/c_1012735/ald-hors-liste-syndromes-de-stevens-johnson-et-de-lyell
http://www.has-sante.fr/portail/jcms/c_1012776/ald-hors-liste-pnds-sur-les-syndromes-de-stevens-johnson-et-de-lyell
http://www.has-sante.fr/portail/jcms/c_1012781/ald-hors-liste-liste-des-actes-et-prestations-sur-les-syndromes-de-stevens-johnson-et-de-lyell
2017
false
false
France
French
watchful waiting
general practice
general practitioners
stevens-johnson syndrome
stevens-johnson syndrome
continuity of patient care
practice guideline

---
Summary Safety Review - PERJETA (pertuzumab) - Assessing the Potential Risk of Stevens-Johnson Syndrome
http://www.hc-sc.gc.ca/dhp-mps/medeff/reviews-examens/perjeta-fra.php
2016
false
false
false
Canada
French
English
pertuzumab
pertuzumab
pertuzumab
risk assessment
breast neoplasms
pharmacovigilance
drug information
stevens-johnson syndrome
antineoplastic agents
antineoplastic agents
antineoplastic combined chemotherapy protocols
antibodies, monoclonal, humanized
antibodies, monoclonal, humanized

---
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108225/
2016
false
false
false
United States of America
French
journal article
epidermis
stevens-johnson syndrome
epidermal necrolysis, toxic

---
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2014/39581a-fra.php
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2014/39583a-fra.php
Canada
English
French
pharmacovigilance note
patient education handout
panitumumab
infusions, intravenous
antineoplastic agents
stevens-johnson syndrome
epidermal necrolysis, toxic
risk
colorectal neoplasms
neoplasm metastasis
antibodies, monoclonal
Panitumumab

---
http://www.dermis.net/dermisroot/fr/30254/diagnose.htm
false
true
false
Germany
stevens-johnson syndrome
image
scientific and technical information

---
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2013/35473a-fra.php
2013
false
Canada
French
English
sunitinib malate
administration, oral
stevens-johnson syndrome
sunitinib
antineoplastic agents
pharmacovigilance note
indoles
pyrroles
Sunitinib

---
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2013/23481a-fra.php
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2013/23483a-fra.php
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2013/23481a-eng.php
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2013/23483a-eng.php
2013
false
Canada
English
French
drug hypersensitivity syndrome
telaprevir
telaprevir
drug therapy, combination
hepatitis C, chronic
serine proteinase inhibitors
canada
pharmacovigilance note
patient education handout
eosinophilia
drug hypersensitivity
stevens-johnson syndrome
syndrome
oligopeptides
Drug reaction with eosinophilia and systemic symptoms

---
https://www.revmed.ch/RMS/2013/RMS-382/Formes-severes-d-hypersensibilite-medicamenteuse-retardee
2013
Switzerland
French
drug hypersensitivity syndrome
journal article
acute generalized exanthematous pustulosis
stevens-johnson syndrome
stevens-johnson syndrome
drug hypersensitivity
drug hypersensitivity

---
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2013/37047a-fra.php
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2013/37049a-fra.php
2013
false
Canada
French
English
Capecitabine
capecitabine
administration, oral
stevens-johnson syndrome
colorectal neoplasms
antimetabolites, antineoplastic
breast neoplasms
pharmacovigilance note

---
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2013/23231a-fra.php
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2013/23233a-fra.php
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2013/23231a-eng.php
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2013/23233a-eng.php
2013
false
Canada
French
English
Rituximab
rituximab
stevens-johnson syndrome
pharmacovigilance note
patient education handout
antineoplastic agents
antirheumatic agents
antigens, CD20
infusions, intravenous
canada

---
http://www.amalyste.fr/
France
French
stevens-johnson syndrome
association of patients

---
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=95455
http://www.orpha.net/data/patho/Pro/fr/LyellStevensJohnson-FRfrPro12597.pdf
http://www.orpha.net/data/patho/Pro/fr/Urgences_NecrolyseEpidermiqueToxique.pdf
2012
France
French
stevens-johnson syndrome
stevens-johnson syndrome
stevens-johnson syndrome
stevens-johnson syndrome
emergency treatment
practice guideline

---
http://www.dermis.net/dermisroot/fr/29169/diagnose.htm
Germany
French
stevens-johnson syndrome
diagnosis, differential
image
scientific and technical information

---
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2009/14060a-fra.php
http://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2009/14580a-fra.php
2009
false
Canada
French
English
Erlotinib Hydrochloride
Tyrosine Kinase Inhibitors
protein kinase inhibitors
intestinal perforation
stevens-johnson syndrome
corneal diseases
pharmacovigilance note
ErbB Receptors

---
http://www.cochrane.org/fr/CD001435
2009
false
true
false
United Kingdom
France
stevens-johnson syndrome
treatment outcome
review of literature
french abstract

---
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=537
https://www.orpha.net/data/patho/Pro/fr/LyellStevensJohnson-FRfrPro12597.pdf
2009
France
French
stevens-johnson syndrome
scientific and technical information

---
http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=FR&Expert=36426
2009
false
true
false
France
scientific and technical information
stevens-johnson syndrome

---
https://www.therapeutique-dermatologique.org/spip.php?article1202
2008
France
scientific and technical information
epidermis
stevens-johnson syndrome

---
http://revmed.ch/RMS/2007/RMS-109/32269
2007
Switzerland
French
stevens-johnson syndrome
stevens-johnson syndrome
diagnosis, differential
stevens-johnson syndrome
stevens-johnson syndrome
precipitating factors
stevens-johnson syndrome
signs and symptoms
journal article
image
case reports

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02/06/2024


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