ICD-11 code : EB13.1;
Preferred Label : Toxic epidermal necrolysis;
ICD-11 definition : Toxic epidermal necrolysis (TEN) is an acute life-threatening skin disease with commonly
quoted overall risk of mortality of between 25 and 30%, though the risk of fatal outcome
is around 90% in the most severely affected patients (SCORTEN score 5). It is characterized
by the rapid onset of extensive erythema, necrosis, and bullous detachment of the
epidermis ( 30% body surface area). Commonly, the mucous membranes are also involved.
Death may result from a combination of sepsis, fluid depletion and multi-organ failure.
In two thirds of cases, TEN is triggered by a clearly identifiable drug allergy.;
ICD-11 synonym : TEN - [toxic epidermal necrolysis]; Lyell syndrome (toxic epidermal necrolysis); Lyell syndrome;
ICD-11 acronym : TEN;
Origin ID : 1575072695;
Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- ICD-10 Mapping
Toxic epidermal necrolysis (TEN) is an acute life-threatening skin disease with commonly
quoted overall risk of mortality of between 25 and 30%, though the risk of fatal outcome
is around 90% in the most severely affected patients (SCORTEN score 5). It is characterized
by the rapid onset of extensive erythema, necrosis, and bullous detachment of the
epidermis ( 30% body surface area). Commonly, the mucous membranes are also involved.
Death may result from a combination of sepsis, fluid depletion and multi-organ failure.
In two thirds of cases, TEN is triggered by a clearly identifiable drug allergy.
