ivermectin - CISMeF

Preferred Label : ivermectin;

MeSH definition : A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.;

CISMeF synonym : ivermectin merck brand; merck brand of ivermectin;

MeSH hyponym : eqvalan; MK-933; stromectol; ivomec; mectizan; MK 933; MK933;

MeSH CAS label : ivermectin;

Registry Number MeSH : 70288-86-7;

Wikipedia link : https://en.wikipedia.org/wiki/Ivermectin;

Codes EINECS : 274-536-0;

Is substance : O;

InChIKey : SPBDXSGPUHCETR-VHJJIYNUSA-N;

Details

Origin ID

D007559;

UMLS CUI

C0022322;

ATC code(s)
- avermectines [ATC Code]
- ivermectin [ATC Code]
- ivermectin [ATC Code]
ATC code(s)
- avermectines [ATC Code]
- ivermectin [ATC Code]
- ivermectin [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
CISMeF manual mappings
- ivermectin [Substance BNPC]
Pharmacological action(s)
- antiparasitic agents [MeSH Descriptor]
- insecticides [MeSH Descriptor]
Record concept(s)
- MK-933 [MeSH concept]
- eqvalan [MeSH concept]
- ivermectin [MeSH concept]
- ivomec [MeSH concept]
- mectizan [MeSH concept]
- stromectol [MeSH concept]
Related MeSH Supplementary Concept(s)
- 1,19-seco-avermectin [MeSH Supplementary Concept]
- 22,23-dihydro-13-O-((2-methoxyethoxy)-methyl)abamectin B(1b) aglycone [MeSH Supplementary Concept]
- 22,23-dihydro-13-O-((2-methoxyethoxy)methyl)abamectin B(1a) aglycone [MeSH Supplementary Concept]
- 22,23-dihydroavermectin B(1)a [MeSH Supplementary Concept]
- 22,23-dihydroavermectin B(1a)-4''-(4-((4-(ethyl(1,2,3,4-tetrahydro-1,4-dioxo-6-phthalazinyl)amino)butyl)amino)-4-oxobutanoate) [MeSH Supplementary Concept]
- 27-hydroxyavermectin [MeSH Supplementary Concept]
- 4''-5,7-dimethylbodipypropionylivermectin [MeSH Supplementary Concept]
- 4''-oxo-avermectin [MeSH Supplementary Concept]
- 4'-amino-4'-avermectin B1 benzoate [MeSH Supplementary Concept]
- 4'-deoleandrosyl-6,8a- seco-6,8a-deoxyavermectin B1a [MeSH Supplementary Concept]
- 4'-deoleandrosyl-6,8a-seco-6,8a-deoxyavermectin A1a [MeSH Supplementary Concept]
- 6,8a-seco-6,8a-deoxyavermectin B1a aglycone [MeSH Supplementary Concept]
- L 648548 [MeSH Supplementary Concept]
- UK 71647 [MeSH Supplementary Concept]
- abamectin [MeSH Supplementary Concept]
- avermectin [MeSH Supplementary Concept]
- avermectin B(1)a [MeSH Supplementary Concept]
- avermectin B2a [MeSH Supplementary Concept]
- avermectin H2B1b [MeSH Supplementary Concept]
- demethylavermectins [MeSH Supplementary Concept]
- desmethylamino-emamectin B1a [MeSH Supplementary Concept]
- doramectin [MeSH Supplementary Concept]
- emamectin [MeSH Supplementary Concept]
- emamectin benzoate [MeSH Supplementary Concept]
- eprinomectin [MeSH Supplementary Concept]
- selamectin [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Ivermectin [ICD-11 Extension code]
- Ivermectin [NCIt concept]
- Ivermectin (substance) [SNOMED CT concept]
- Product containing ivermectin (medicinal product) [SNOMED CT concept]
- ivermectin [ATC Code]
- ivermectin [ATC Code]
- ivermectin [Substance BNPC]
- ivermectin [SNOMED Notion]
Validated automatic mappings to BTNT
- ivermectin [ATC Code]
- ivermectin [ATC Code]

Keyword's position in hierarchy(ies) :

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