ICD-11 code : EB13;
Preferred Label : Stevens-Johnson syndrome or toxic epidermal necrolysis;
ICD-11 definition : A spectrum of severe and life-threatening hypersensitivity disorders affecting skin
and mucous membranes, most commonly precipitated by an idiosyncratic reaction to medication.
Stevens-Johnson syndrome (SJS) always involves mucosal surfaces but the skin involvement
is limited by definition to 10% body surface area (BSA). Toxic epidermal necrolysis
(TEN) may sometimes spare mucous membranes but skin involvement is by definition
30% BSA. An intermediate form is recognized in which mucosal involvement is accompanied
by skin involvement of 10-30% BSA (SJS-TEN overlap syndrome). All forms result in
extensive sloughing and ulceration and carry a significant risk of fatal outcome.;
ICD-11 synonym : SJS/TEN - [Stevens-Johnson syndrome and toxic epidermal necrolysis]; Stevens-Johnson syndrome and toxic epidermal necrolysis;
ICD-11 acronym : SJS/TEN;
Origin ID : 195467267;
Automatic exact mappings (from CISMeF team)
A spectrum of severe and life-threatening hypersensitivity disorders affecting skin
and mucous membranes, most commonly precipitated by an idiosyncratic reaction to medication.
Stevens-Johnson syndrome (SJS) always involves mucosal surfaces but the skin involvement
is limited by definition to 10% body surface area (BSA). Toxic epidermal necrolysis
(TEN) may sometimes spare mucous membranes but skin involvement is by definition
30% BSA. An intermediate form is recognized in which mucosal involvement is accompanied
by skin involvement of 10-30% BSA (SJS-TEN overlap syndrome). All forms result in
extensive sloughing and ulceration and carry a significant risk of fatal outcome.
