Preferred Label : Stevens-Johnson Syndrome;
NCIt related terms : Stevens Johnson Syndrome;
NCIt definition : A systemic, serious, and life-threatening disorder characterized by lesions in the
skin and mucous membranes that may lead to necrosis. The lesions may appear anywhere
in the body but they occur more commonly in the palms, soles, dorsum of the hands,
and extensor surfaces. The lesions are vesicular or necrotic in the center, surrounded
by an erythematous zone and occupy less than 10% of the body surfaces. The appearance
of the mucocutaneous lesions is preceded by an upper respiratory tract infection.
It is an immune complex hypersensitivity reaction usually caused by drugs (e.g., sulfa,
phenytoin, penicillin), viruses (e.g., herpes simplex, influenza, hepatitis), and
malignancies (e.g., carcinoma and lymphoma).;
Alternative definition : CTCAE: A disorder characterized by less than 10% total body skin area separation of
dermis. The syndrome is thought to be a hypersensitivity complex affecting the skin
and the mucous membranes.; NICHD: Drug or microbial induced exanthem characterized by papular or target-like
lesions that involve less than 10% of the skin surface and at least two mucous membranes
associated with systemic symptoms and may result in variable areas of skin necrosis.;
Codes from synonyms : E13736;
Origin ID : C79484;
UMLS CUI : C0038325;
Currated CISMeF NLP mapping
DO Cross reference
Has associated anatomic sites
Semantic type(s)
UMLS correspondences (same concept)
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