NCIt definition : Human IL1A wild-type allele is located within 2q14 and is approximately 11 kb in length.
This allele, which encodes interleukin-1 alpha protein, plays a role in various immune
responses, inflammatory processes and hematopoiesis.;
NCIt note : IL1A and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome
2. It has been suggested that the polymorphism of these genes is associated with rheumatoid
arthritis and Alzheimer's disease.;