T-Cell Surface Glycoprotein CD3 Zeta Chain

Preferred Label : T-Cell Surface Glycoprotein CD3 Zeta Chain;

NCIt synonyms : CD3z; CD-3-Zeta; T-Cell Receptor T3 Zeta Chain; CD247; CD3-Zeta; T-Cell Receptor-T3 Zeta Chain;

NCIt definition : T-cell surface glycoprotein CD3 zeta chain (164 aa, 18 kDa) is encoded by the human CD247 gene. This protein is involved in T-cell intracellular signaling.;

Details

Origin ID

C38903;

UMLS CUI

C1515135;

OMIM relation
- Cd247 antigen [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CD247 Gene [NCIt concept]
- Immunoprotein Gene [NCIt concept]
gene_product_has_chemical_classification
- Protein Complex Subunit [NCIt concept]
gene_product_is_element_in_pathway
- CSK Protein Kinase Activation Pathway [NCIt concept]
- CTL-mediated Immune Response Pathway [NCIt concept]
- CXCR4-Mediated Signaling Pathway [NCIt concept]
- Chagas Disease Pathway [NCIt concept]
- Cytotoxic T Cell Surface Pathway [NCIt concept]
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- HIV Induced T Cell Apoptosis Pathway [NCIt concept]
- HIV-1 Nef: Negative Effector Pathway for Fas and TNF-Alpha [NCIt concept]
- IL12 Signaling Pathway [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- IL17 Signaling Pathway [NCIt concept]
- NO2-Dependent IL12 Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Stathmin Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway BioCarta [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- T Cell Receptor and CD3 Complex Signaling Pathway [NCIt concept]
- T Helper Cell Surface Molecule Pathway [NCIt concept]
- T-Cell Activation Co-Stimulatory Signaling Pathway [NCIt concept]
- T-Cell Activation Pathway [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD4+ T Cells [NCIt concept]
- T-Cell Receptor Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- TCR Activation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Immune System Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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