Elongation Factor 2

Preferred Label : Elongation Factor 2;

NCIt synonyms : Polypeptidyl-tRNA Translocase; EF2; EEF2; Eukaryotic Translation Elongation Factor 2; Elongation Factor-2; EF-2;

NCIt definition : Elongation factor 2 (858 aa, 95 kDa) is encoded by the human EEF2 gene. This protein plays a role in the GTP-dependent ribosomal A-site to P-site translocation of nascent protein chains.;

Details

Origin ID

C38586;

UMLS CUI

C4721670;

OMIM relation
- Eukaryotic translation elongation factor 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- peptide elongation factor 2 [MeSH concept]
- peptide elongation factor 2 [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- EEF2 Gene [NCIt concept]
- Translation Process Gene [NCIt concept]
gene_product_affected_by_chemical_or_drug
- BL22 Immunotoxin [NCIt concept]
- DTA-H19 Plasmid [NCIt concept]
- ERB-38 Immunotoxin [NCIt concept]
- LMB-1 Immunotoxin [NCIt concept]
- LMB-2 Immunotoxin [NCIt concept]
- LMB-7 Immunotoxin [NCIt concept]
- LMB-9 Immunotoxin [NCIt concept]
- Moxetumomab Pasudotox [NCIt concept]
- Tagraxofusp-erzs [NCIt concept]
gene_product_has_biochemical_function
- GTPase [NCIt concept]
- Translation Process Protein [NCIt concept]
gene_product_is_element_in_pathway
- Protein Translation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Translation Process [NCIt concept]
is_target
- LMB-2 Immunotoxin [NCIt concept]
- Tagraxofusp-erzs [NCIt concept]

Keyword's position in hierarchy(ies) :

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