Eukaryotic Translation Initiation Factor 4E

Preferred Label : Eukaryotic Translation Initiation Factor 4E;

NCIt synonyms : eIF-4F 25 kDa Subunit; eIF4E; mRNA Cap-Binding Protein; Eukaryotic Translation Initiation Factor 4E-Like 1; eIF-4E;

NCIt definition : Eukaryotic translation initiation factor 4E (217 aa, 25 kDa) is encoded by the human EIF4E gene. This protein is involved in the initiation of mRNA translation.;

Details

Origin ID

C105125;

UMLS CUI

C3539642;

Automatic exact mappings (from CISMeF team)
- Eukaryotic translation initiation factor 4E [ORDO Gene]
- Eukaryotic translation initiation factor 4e [OMIM gene]
- eIF-4 [MeSH Supplementary Concept]
- eIF-4 [MeSH concept]
- eukaryotic initiation Factor-4E [MeSH Descriptor]
- eukaryotic translation initiation factor 4E [HGNC gene]
- rna cap-binding proteins [MeSH Descriptor]
OMIM relation
- Eukaryotic translation initiation factor 4e [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- EIF4E Gene [NCIt concept]
- Translation Process Gene [NCIt concept]
gene_product_has_biochemical_function
- RNA Binding Protein [NCIt concept]
gene_product_is_element_in_pathway
- Hepatocyte Growth Factor Receptor Signaling Pathway PID [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Internal Ribosome Entry Pathway [NCIt concept]
- Protein Translation Pathway [NCIt concept]
- Skeletal Muscle Hypertrophy Pathway [NCIt concept]
- eIF4 Regulation Pathway [NCIt concept]
- mTOR Signaling Pathway BioCarta [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
- mTOR Signaling Pathway PID [NCIt concept]
- p38-alpha and p38-beta Signaling Pathway [NCIt concept]
gene_product_is_physical_part_of
- Eukaryotic Translation Initiation Factor 4F [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling Process [NCIt concept]
- Positive Regulation of Mitosis [NCIt concept]
- RNA Binding [NCIt concept]
- Translation Initiation [NCIt concept]
- Translation Process [NCIt concept]
- mRNA Export [NCIt concept]
is_target
- eIF4E Antisense Oligonucleotide ISIS 183750 [NCIt concept]

Keyword's position in hierarchy(ies) :

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